Peptide

TB-500

Thymosin Beta-4 — for deep tissue regeneration.

$100 5 mg vial
TB-500
Overview

What It Is

TB-500 is a synthetic fragment of the naturally occurring protein Thymosin Beta-4, prescribed to support cellular repair, flexibility, and full-body recovery. Frequently paired with BPC-157 for a comprehensive regenerative protocol.

  • Promotes new blood vessel and muscle cell growth
  • Improves flexibility and reduces stiffness
  • Supports wound healing and tissue remodeling
  • Reduces inflammation systemically
The Mechanism

The Mechanism, In Plain Clinical Terms

  • TB-500 is a synthetic version of the active region of Thymosin Beta-4, a naturally occurring protein present in nearly every human cell. It binds G-actin to regulate cytoskeletal remodeling, cell migration, and angiogenesis — the biological infrastructure of wound repair.
Evidence

What The Peer-Reviewed Literature Shows

Thymosin Beta-4: A Multi-Functional Regenerative Peptide

Goldstein et al., Expert Opinion on Biological Therapy, 2012

Comprehensive review of TB-4 across cardiac, dermal, corneal, and CNS repair models — consistent evidence of accelerated tissue regeneration and reduced fibrosis.

Thymosin Beta-4 for Dry Eye Disease (RGN-259)

Sosne et al., Annals of the New York Academy of Sciences, 2015

Phase II human trials demonstrated statistically significant improvement in dry eye symptoms and corneal epithelial healing versus placebo.

Thymosin Beta-4 Promotes Cardiac Repair

Bock-Marquette et al., Nature, 2004

Landmark study showing TB-4 preserves cardiomyocytes and stimulates coronary vessel growth after myocardial infarction in animal models.

Protocol

Prescribed Responsibly. Monitored Throughout.

Physician-supervised subcutaneous injection protocol, typically 4–6 weeks loading with a lower maintenance phase. Custom dosing based on your clinical goals.

Ideal For

  • Chronic injury or slow healing
  • Athletes seeking systemic recovery
  • Post-surgical rehabilitation
  • Anti-inflammatory optimization

Safety

  • Not FDA-approved; compounded and dispensed by prescription only.
  • Contraindicated in pregnancy, breastfeeding, and active cancer.
  • Most common effects: transient fatigue and mild injection-site reaction.
  • Athletes should note WADA prohibits TB-500 in competition.
Questions

Your Questions, Answered

How is TB-500 different from BPC-157?

BPC-157 is highly localized in its tissue-repair action; TB-500 works more systemically via cell migration and angiogenesis. They are complementary and often prescribed together.

How long is a full cycle?

A typical loading phase is 4–6 weeks with a lower-dose maintenance phase thereafter, based on your clinical response.

Can it be used post-surgery?

Only with clearance from your surgeon. We coordinate with your surgical team before starting any post-operative regenerative protocol.

Begin

Prescribed With Care

Every protocol is prescribed and monitored by our clinical team.